LRPPRC 抗体 (AA 847-876)
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北京 101111
Quick Overview for LRPPRC 抗体 (AA 847-876) (ABIN6243782)
抗原
See all LRPPRC 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 847-876
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预测反应
- Rat
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This LRPPRC antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 847-876 amino acids from the Central region of human LRPPRC.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- LRPPRC (Leucine-Rich PPR-Motif Containing (LRPPRC))
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别名
- LRPPRC
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背景
- May play a role in RNA metabolism in both nuclei and mitochondria. In the nucleus binds to HNRPA1-associated poly(A) mRNAs and is part of nmRNP complexes at late stages of mRNA maturation which are possibly associated with nuclear mRNA export. May bind mature mRNA in the nucleus outer membrane. In mitochondria binds to poly(A) mRNA. Plays a role in translation or stability of mitochondrially encoded cytochrome c oxidase (COX) subunits. May be involved in transcription regulation. Cooperates with PPARGC1A to regulate certain mitochondrially encoded genes and gluconeogenic genes and may regulate docking of PPARGC1A to transcription factors. Seems to be involved in the transcription regulation of the multidrug-related genes MDR1 and MVP. Part of a nuclear factor that binds to the invMED1 element of MDR1 and MVP gene promoters. Binds single-stranded DNA (By similarity).
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分子量
- 157905
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UniProt
- P42704
抗原
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