NGEF 抗体 (N-Term)
Quick Overview for NGEF 抗体 (N-Term) (ABIN6243778)
抗原
See all NGEF 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 187-220, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This NGEF antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 187-220 amino acids from the N-terminal region of human NGEF.
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亚型
- Ig Fraction
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anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 612-710) antibody
NGEF 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 6E7 unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 495-710) antibodyNGEF 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 669-704), (C-Term) antibodyNGEF 适用: 人 WB 宿主: 兔 Polyclonal RB53235 unconjugated
anti-Neuronal Guanine Nucleotide Exchange Factor (NGEF) (AA 429-710) antibodyNGEF 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- NGEF (Neuronal Guanine Nucleotide Exchange Factor (NGEF))
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别名
- NGEF
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背景
- Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).
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分子量
- 82496
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UniProt
- Q8N5V2
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途径
- Neurotrophin Signaling Pathway
抗原
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