KISS1 抗体 (AA 115-145)
Quick Overview for KISS1 抗体 (AA 115-145) (ABIN6243763)
抗原
See all KISS1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 115-145
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This KISS1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 115-145 amino acids from the human region of human KISS1.
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亚型
- Ig Fraction
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anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 46-145) antibody
KISS1 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F7 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (Internal Region) antibodyKISS1 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-52) antibodyKISS1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB53797 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) antibodyKISS1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-126) antibodyKISS1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) antibodyKISS1 适用: 人 WB, IHC 宿主: 小鼠 Monoclonal C1 unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 20-138) antibodyKISS1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) antibodyKISS1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-138) antibodyKISS1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-KiSS-1 Metastasis-Suppressor (KISS1) (AA 1-138) antibodyKISS1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- IF: 1:25. WB: 1:2000. WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- KISS1 (KiSS-1 Metastasis-Suppressor (KISS1))
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别名
- KISS1
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背景
- Metastasis suppressor protein in malignant melanomas and in some breast cancers. May regulate events downstream of cell- matrix adhesion, perhaps involving cytoskeletal reorganization. Generates a C-terminally amidated peptide, metastin which functions as the endogenous ligand of the G-protein coupled receptor GPR54. Activation of the receptor inhibits cell proliferation and cell migration, key characteristics of tumor metastasis. Kp-10 is a decapeptide derived from the primary translation product, isolated in conditioned medium of first trimester trophoblast. Kp-10, but not other kisspeptins, increased intracellular Ca(2+) levels in isolated first trimester trophoblasts. Kp-10 is a paracrine/endocrine regulator in fine- tuning trophoblast invasion generated by the trophoblast itself. The receptor is also essential for normal gonadotropin-released hormone physiology and for puberty. The hypothalamic KiSS1/GPR54 system is a pivotal factor in central regulation of the gonadotropic axis at puberty and in adulthood.
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分子量
- 14705
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UniProt
- Q15726
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途径
- Positive Regulation of Peptide Hormone Secretion
抗原
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