KDM6A 抗体 (AA 797-832)
Quick Overview for KDM6A 抗体 (AA 797-832) (ABIN6243759)
抗原
See all KDM6A 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 797-832
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This KDM6A antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 797-832 amino acids from the Central region of human KDM6A.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- KDM6A (Lysine (K)-Specific Demethylase 6A (KDM6A))
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别名
- KDM6A
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背景
- Histone demethylase that specifically demethylates 'Lys- 27' of histone H3, thereby playing a central role in histone code. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27'. Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A.
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分子量
- 154177
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UniProt
- O15550
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途径
- Tube Formation, Warburg Effect
抗原
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