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Transferrin Receptor 抗体 (AA 649-677)

The 小鼠 单克隆 anti-Transferrin Receptor antibody is suitable to detect Transferrin Receptor in samples from 人. It has been validated for WB.
产品编号 ABIN6243624
发货至: 中国
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Quick Overview for Transferrin Receptor 抗体 (AA 649-677) (ABIN6243624)

抗原

See all Transferrin Receptor (TFRC) 抗体
Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This Transferrin Receptor antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

514CT23-4-1
  • 抗原表位

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    AA 649-677

    纯化方法

    This antibody is prepared by Euglobin precipitation followed by dialysis against PBS.

    免疫原

    This TFRC antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 649-677 amino acids from human TFRC.

    亚型

    IgM
  • 应用备注

    WB: 1:1000. WB: 1:100~250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    Transferrin Receptor (TFRC) (Transferrin Receptor (p90, CD71) (TFRC))

    别名

    TFRC

    背景

    Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site.

    分子量

    84871

    NCBI登录号

    NP_001121620, NP_003225

    UniProt

    P02786

    途径

    Transition Metal Ion Homeostasis
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