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ITGA7 抗体 (C-Term)

This anti-ITGA7 antibody is a 兔 多克隆 antibody detecting ITGA7 in WB. Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6243591
发货至: 中国

Quick Overview for ITGA7 抗体 (C-Term) (ABIN6243591)

抗原

See all ITGA7 抗体
ITGA7 (Integrin, alpha 7 (ITGA7))

适用

  • 44
  • 19
  • 6
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1

宿主

  • 40
  • 8
  • 1

克隆类型

  • 41
  • 8
多克隆

标记

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  • 1
  • 1
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  • 1
  • 1
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This ITGA7 antibody is un-conjugated

应用范围

  • 31
  • 21
  • 7
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB52832
  • 抗原表位

    • 11
    • 7
    • 5
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1149-1181, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This ITGA7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1149-1181 amino acids from the C-terminal region of human ITGA7.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:8000. WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Ming, Fu, Zhang, Qin, Cao, Chan, Ma, Xie, Guan: "Integrin α7 is a functional cancer stem cell surface marker in oesophageal squamous cell carcinoma." in: Nature communications, Vol. 7, pp. 13568, (2018) (PubMed).

  • 抗原

    ITGA7 (Integrin, alpha 7 (ITGA7))

    别名

    ITGA7

    背景

    Integrin alpha-7/beta-1 is the primary laminin receptor on skeletal myoblasts and adult myofibers. During myogenic differentiation, it may induce changes in the shape and mobility of myoblasts, and facilitate their localization at laminin-rich sites of secondary fiber formation. It is involved in the maintenance of the myofibers cytoarchitecture as well as for their anchorage, viability and functional integrity. Isoform Alpha-7X2B and isoform Alpha-7X1B promote myoblast migration on laminin 1 and laminin 2/4, but isoform Alpha-7X1B is less active on laminin 1 (In vitro). Acts as Schwann cell receptor for laminin-2. Acts as a receptor of COMP and mediates its effect on vascular smooth muscle cells (VSMCs) maturation (By similarity). Required to promote contractile phenotype acquisition in differentiated airway smooth muscle (ASM) cells.

    分子量

    128948

    UniProt

    Q13683

    途径

    Integrin Complex
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