PIK3R2 抗体 (AA 430-470)
Quick Overview for PIK3R2 抗体 (AA 430-470) (ABIN6243583)
抗原
See all PIK3R2 (PI3K p85b) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 430-470
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 430-470 amino acids from human.
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亚型
- Ig Fraction
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anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-60) antibody
PI3K p85b 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人 WB, IHC 宿主: 兔 Monoclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 75-125), (Regulatory Subunit beta) antibodyPI3K p85b 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠, Cow, 犬 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Subunit beta) antibodyPI3K p85b 适用: 人, Cow, 猴 WB, IP, IHC (fro) 宿主: 小鼠 Monoclonal T15 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Thr232) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (Tyr467) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 447-461), (Middle Region) antibodyPI3K p85b 适用: 人, 大鼠, 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 445-474) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB13091 unconjugated
anti-Phosphoinositide 3 Kinase, p85 beta (PI3K p85b) (AA 1-30), (N-Term) antibodyPI3K p85b 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB11635 unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- PIK3R2 (PI3K p85b) (Phosphoinositide 3 Kinase, p85 beta (PI3K p85b))
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别名
- PIK3R2
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背景
- Regulatory subunit of phosphoinositide-3-kinase (PI3K), a kinase that phosphorylates PtdIns(4,5)P2 (Phosphatidylinositol 4,5-bisphosphate) to generate phosphatidylinositol 3,4,5- trisphosphate (PIP3). PIP3 plays a key role by recruiting PH domain-containing proteins to the membrane, including AKT1 and PDPK1, activating signaling cascades involved in cell growth, survival, proliferation, motility and morphology. Binds to activated (phosphorylated) protein-tyrosine kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. Indirectly regulates autophagy (PubMed:< a href="http://www.uniprot.org/citations/23604317" target="_blank">23604317). Promotes nuclear translocation of XBP1 isoform 2 in a ER stress- and/or insulin- dependent manner during metabolic overloading in the liver and hence plays a role in glucose tolerance improvement (By similarity).
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分子量
- 81545
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UniProt
- O00459
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途径
- VEGF Signaling, BCR Signaling
抗原
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