ADAM15 抗体 (AA 37-72)
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北京 101111
Quick Overview for ADAM15 抗体 (AA 37-72) (ABIN6243467)
抗原
See all ADAM15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 37-72
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ADAM15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 37-72 amino acids of human ADAM15.
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亚型
- IgG
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))
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别名
- ADAM15
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背景
- Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.
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分子量
- 92959
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UniProt
- Q13444
抗原
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