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METTL14 抗体 (AA 2-36)

The 兔 多克隆 anti-METTL14 antibody is suitable to detect METTL14 in samples from 人 和 小鼠. It has been validated for WB, IF 和 IHC (p).
产品编号 ABIN6243447
发货至: 中国
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Room 801-803
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Quick Overview for METTL14 抗体 (AA 2-36) (ABIN6243447)

抗原

See all METTL14 抗体
METTL14 (Methyltransferase Like 14 (METTL14))

适用

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人, 小鼠

宿主

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克隆类型

  • 30
多克隆

标记

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This METTL14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB55130
  • 抗原表位

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    AA 2-36

    预测反应

    B

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This METTL14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 2-36 amino acids from the human region of human METTL14.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. IHC-P: 1:250

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    METTL14 (Methyltransferase Like 14 (METTL14))

    别名

    METTL14

    背景

    N6-methyltransferase that methylates adenosine residues of some mRNAs and acts as a regulator of the circadian clock and self-renewal of embryonic stem cells. N6-methyladenosine (m6A), which takes place at the 5'-[AG]GAC-3' consensus sites of some mRNAs, plays a role in the efficiency of mRNA splicing and processing and mRNA stability. M6A regulates the length of the circadian clock: acts as a early pace-setter in the circadian loop M6A also acts as a regulator of mRNA stability: in embryonic stem cells (ESCs), m6A methylation of mRNAs encoding developmental regulators, results in transcript destabilization, maintaining the groung state of ESCs, thereby promoting self-renewal of ESCs.

    分子量

    52150

    UniProt

    Q9HCE5
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