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CBX7 抗体 (C-Term)

CBX7 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal RB50982 unconjugated
产品编号 ABIN6243434
发货至: 中国
  • 抗原 See all CBX7 抗体
    CBX7 (Chromobox Homolog 7 (CBX7))
    抗原表位
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 144-178, C-Term
    适用
    • 36
    • 5
    • 5
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 28
    • 7
    • 1
    克隆类型
    • 23
    • 13
    多克隆
    标记
    • 22
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This CBX7 antibody is un-conjugated
    应用范围
    • 20
    • 10
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    纯化方法
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    免疫原
    This Mouse Cbx7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 144-178 amino acids from the C-terminal region of human Mouse Cbx7.
    克隆位点
    RB50982
    亚型
    Ig Fraction
    Top Product
    Discover our top product CBX7 Primary Antibody
  • 应用备注
    WB: 1:1000
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    有效期
    6 months
  • 抗原
    CBX7 (Chromobox Homolog 7 (CBX7))
    别名
    Cbx7 (CBX7 产品)
    别名
    1600014J01Rik antibody, AI851678 antibody, D15Ertd417e antibody, zgc:110152 antibody, chromobox 7 antibody, chromobox homolog 7a antibody, CBX7 antibody, Cbx7 antibody, cbx7a antibody
    背景
    Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to histone H3 trimethylated 'Lys-9' (H3K9me3) or at 'Lys-27' (H3K27me3). May possibly also bind trimethylated lysine residues in other proteins (in vitro). Binds non-coding, single-stranded RNA. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
    分子量
    18109
    UniProt
    Q8VDS3
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