CTCFL 抗体 (AA 617-650)
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Quick Overview for CTCFL 抗体 (AA 617-650) (ABIN6243421)
抗原
See all CTCFL 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 617-650
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CTCFL antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 617-650 amino acids from human CTCFL.
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亚型
- Ig Fraction
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anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-270) antibody
CTCFL 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (N-Term) antibodyCTCFL 适用: 人 WB, ChIP-seq, ChIP 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-270) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-636) antibodyCTCFL 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 211-260) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 36-85) antibodyCTCFL 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) antibodyCTCFL 适用: 人, 小鼠, 大鼠 WB, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL) (AA 1-30) antibodyCTCFL 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- CTCFL (CCCTC-Binding Factor (Zinc Finger Protein)-Like (CTCFL))
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别名
- CTCFL
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背景
- Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 'Arg-3' to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters.
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分子量
- 75747
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UniProt
- Q8NI51
抗原
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