UHMK1 抗体 (C-Term)
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Quick Overview for UHMK1 抗体 (C-Term) (ABIN6243411)
抗原
See all UHMK1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 265-295, C-Term
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预测反应
- Rat
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-295 amino acids from the C-terminal region of human KIST (KIS).
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- UHMK1 (U2AF Homology Motif (UHM) Kinase 1 (UHMK1))
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别名
- KIST (KIS)
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背景
- KIST, a member of the Ser/Thr protein kinase family, is a pyruvate kinase that catalyzes formation of phosphoenolpyruvate from pyruvate and ATP. A role for the primarily nuclear KIST protein in mediation of cellular metabolism has been postulated based on the interaction identified with thyroid hormone. KIST is widely expressed, with highest abundance in skeletal muscle, kidney, placenta and peripheral blood leukocytes. Upon serum stimulation, KIST phosphorylates CDKN1B/p27Kip1, thereby regulating the subcellular location of CDKN1B and cell cycle progression in the G1 phase. KIST, which contains one RNA recognition motif domain, has been proposed to partipate in trafficking and processing of RNA. KIST binds to Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells.
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分子量
- 46546
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NCBI登录号
- NP_001171692, NP_653225, NP_787062
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UniProt
- Q8TAS1
抗原
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