FER 抗体
Quick Overview for FER 抗体 (ABIN6243361)
抗原
See all FER 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
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免疫原
- This Fer antibody is generated from a mouse immunized with a recombinant protein.
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亚型
- IgG2a kappa
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anti-FER Tyrosine Kinase (FER) antibody
FER 适用: 人, 小鼠 WB, ELISA, IHC, ICC 宿主: 小鼠 Monoclonal 5D2C4 unconjugated
anti-FER Tyrosine Kinase (FER) (AA 1-300) antibodyFER 适用: 人, 小鼠 WB, IHC (p) 宿主: 小鼠 Monoclonal 1457CT181-12-17 unconjugated
anti-FER Tyrosine Kinase (FER) (AA 782-811), (C-Term) antibodyFER 适用: 人 WB, IF, IHC (p), FACS 宿主: 兔 Polyclonal RB03222 unconjugated
anti-FER Tyrosine Kinase (FER) antibodyFER 适用: 人, 小鼠, 大鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (Ser376) antibodyFER 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (AA 521-536), (Middle Region) antibodyFER 适用: 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人, 犬, Cow, Pig WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-FER Tyrosine Kinase (FER) (C-Term) antibodyFER 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF: 1:25. WB: 1:4000. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- FER (FER Tyrosine Kinase (FER))
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别名
- Fer
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背景
- Tyrosine-protein kinase that acts downstream of cell surface receptors for growth factors and plays a role in the regulation of the actin cytoskeleton, microtubule assembly, lamellipodia formation, cell adhesion, cell migration and chemotaxis. Acts downstream of EGFR, KIT, PDGFRA and PDGFRB. Acts downstream of EGFR to promote activation of NF-kappa-B and cell proliferation. May play a role in the regulation of the mitotic cell cycle. Plays a role in the insulin receptor signaling pathway and in activation of phosphatidylinositol 3-kinase. Acts downstream of the activated FCER1 receptor and plays a role in FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Plays a role in the regulation of mast cell degranulation. Plays a role in leukocyte recruitment and diapedesis in response to bacterial lipopolysaccharide (LPS). Phosphorylates CTTN, CTNND1, PTK2/FAK1, GAB1, PECAM1 and PTPN11. May phosphorylate JUP and PTPN1. Can phosphorylate STAT3 according to PubMed:< a href="http://www.uniprot.org/citations/10878010" target="_blank">10878010 and PubMed:< a href="http://www.uniprot.org/citations/19159681" target="_blank">19159681, but clearly plays a redundant role in STAT3 phosphorylation. According to PubMed:< a href="http://www.uniprot.org/citations/11134346" target="_blank">11134346, cells where wild type FER has been replaced by a kinase-dead mutant show no reduction in STAT3 phosphorylation. Phosphorylates TMF1. Isoform 3 lacks kinase activity.
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分子量
- 94579
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UniProt
- P70451
抗原
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