UBE2N 抗体 (AA 41-74)
Quick Overview for UBE2N 抗体 (AA 41-74) (ABIN6243322)
抗原
See all UBE2N 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 41-74
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This UBE2N antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 41-74 amino acids from the Central region of human UBE2N.
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亚型
- Ig Fraction
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anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibody
UBE2N 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3G1-D10 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) antibodyUBE2N 适用: 人 WB, IHC, IF 宿主: 兔 Monoclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (Middle Region) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 绵羊, 兔, 马, 豚鼠, Saccharomyces cerevisiae, 山羊 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (Middle Region) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 绵羊, 兔, 马, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 56-152) antibodyUBE2N 适用: 大鼠, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 20-138) antibodyUBE2N 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 4C11-G11 unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 1-152) antibodyUBE2N 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (C-Term) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, Cow, 绵羊, 兔, 马, 豚鼠, Drosophila melanogaster, 小鸡, 非洲爪蟾, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin-Conjugating Enzyme E2N (UBE2N) (AA 80-129) antibodyUBE2N 适用: 人, 大鼠, 小鼠, 斑马鱼, 犬, Cow, 绵羊, 兔, 马, 豚鼠, Drosophila melanogaster, 小鸡, 非洲爪蟾, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. WB: 1:500. WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- UBE2N (Ubiquitin-Conjugating Enzyme E2N (UBE2N))
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别名
- UBE2N
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背景
- The UBE2V1-UBE2N and UBE2V2-UBE2N heterodimers catalyze the synthesis of non-canonical 'Lys-63'-linked polyubiquitin chains. This type of polyubiquitination does not lead to protein degradation by the proteasome. Mediates transcriptional activation of target genes. Plays a role in the control of progress through the cell cycle and differentiation. Plays a role in the error-free DNA repair pathway and contributes to the survival of cells after DNA damage. Acts together with the E3 ligases, HLTF and SHPRH, in the 'Lys-63'-linked poly-ubiquitination of PCNA upon genotoxic stress, which is required for DNA repair. Appears to act together with E3 ligase RNF5 in the 'Lys-63'-linked polyubiquitination of JKAMP thereby regulating JKAMP function by decreasing its association with components of the proteasome and ERAD. Promotes TRIM5 capsid-specific restriction activity and the UBE2V1-UBE2N heterodimer acts in concert with TRIM5 to generate 'Lys-63'-linked polyubiquitin chains which activate the MAP3K7/TAK1 complex which in turn results in the induction and expression of NF-kappa-B and MAPK-responsive inflammatory genes (By similarity).
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分子量
- 17138
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UniProt
- P61088
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途径
- TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Positive Regulation of Response to DNA Damage Stimulus, Ubiquitin Proteasome Pathway
抗原
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