TRRAP 抗体 (C-Term)
This anti-TRRAP antibody is a 兔 多克隆 antibody detecting TRRAP in WB 和 IF. Suitable for 人.
Quick Overview for TRRAP 抗体 (C-Term) (ABIN6243321)
抗原
See all TRRAP 抗体
TRRAP
(Transformation/transcription Domain-Associated Protein (TRRAP))
适用
人
宿主
兔
克隆类型
多克隆
标记
This TRRAP antibody is un-conjugated
应用范围
Western Blotting (WB), Immunofluorescence (IF)
克隆位点
RB51386
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抗原表位
- AA 3015-3049, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TRRAP antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 3015-3049 amino acids from the C-terminal region of human TRRAP.
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亚型
- Ig Fraction
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anti-Transformation/transcription Domain-Associated Protein (TRRAP) (AA 1703-1737), (C-Term) antibody
TRRAP 适用: 小鼠 WB 宿主: 兔 Polyclonal RB51498 unconjugated
anti-Transformation/transcription Domain-Associated Protein (TRRAP) (AA 3534-3770) antibodyTRRAP 适用: 人 WB, IP, IHC, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF: 1:25. WB: 1:2000. WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- TRRAP (Transformation/transcription Domain-Associated Protein (TRRAP))
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别名
- TRRAP
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背景
- Adapter protein, which is found in various multiprotein chromatin complexes with histone acetyltransferase activity (HAT), which gives a specific tag for epigenetic transcription activation. Component of the NuA4 histone acetyltransferase complex which is responsible for acetylation of nucleosomal histones H4 and H2A. Plays a central role in MYC transcription activation, and also participates in cell transformation by MYC. Required for p53/TP53-, E2F1- and E2F4-mediated transcription activation. Also involved in transcription activation mediated by the adenovirus E1A, a viral oncoprotein that deregulates transcription of key genes. Probably acts by linking transcription factors such as E1A, MYC or E2F1 to HAT complexes such as STAGA thereby allowing transcription activation. Probably not required in the steps following histone acetylation in processes of transcription activation. May be required for the mitotic checkpoint and normal cell cycle progression. Component of a SWR1- like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.
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分子量
- 437600
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UniProt
- Q9Y4A5
抗原
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