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HSD17B10 抗体 (AA 14-48)

This anti-HSD17B10 antibody is a 兔 多克隆 antibody detecting HSD17B10 in WB, IF 和 FACS. Suitable for 人.
产品编号 ABIN6243231
发货至: 中国

Quick Overview for HSD17B10 抗体 (AA 14-48) (ABIN6243231)

抗原

See all HSD17B10 抗体
HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

适用

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  • 25
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宿主

  • 49
  • 9
  • 1

克隆类型

  • 51
  • 8
多克隆

标记

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This HSD17B10 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

RB56756
  • 抗原表位

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    AA 14-48

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This HSD17B10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 14-48 amino acids from human HSD17B10.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:25. WB: 1:8000. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

    别名

    HSD17B10

    背景

    Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

    分子量

    26923

    UniProt

    Q99714
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