HSD17B10 抗体 (AA 140-172)
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北京 101111
Quick Overview for HSD17B10 抗体 (AA 140-172) (ABIN6243230)
抗原
See all HSD17B10 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 140-172
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预测反应
- B
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This HSD17B10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 140-172 amino acids from the Central region of human HSD17B10.
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亚型
- Ig Fraction
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应用备注
- IF: 1:25. WB: 1:2000. IHC-P: 1:25. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
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别名
- HSD17B10
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背景
- Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).
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分子量
- 26923
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UniProt
- Q99714
抗原
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