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HSD17B10 抗体 (AA 140-172)

This 兔 多克隆 anti-HSD17B10 antibody (Clone RB56913) specifically detects HSD17B10 in WB, IF, FACS 和 IHC (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN6243230
发货至: 中国
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Quick Overview for HSD17B10 抗体 (AA 140-172) (ABIN6243230)

抗原

See all HSD17B10 抗体
HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

适用

  • 72
  • 33
  • 26
  • 3
  • 2
  • 2
  • 2
人, 小鼠, 大鼠

宿主

  • 63
  • 10
  • 1

克隆类型

  • 56
  • 18
多克隆

标记

  • 40
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
This HSD17B10 antibody is un-conjugated

应用范围

  • 47
  • 31
  • 28
  • 22
  • 19
  • 19
  • 10
  • 5
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB56913
  • 抗原表位

    • 10
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 140-172

    预测反应

    B

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This HSD17B10 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 140-172 amino acids from the Central region of human HSD17B10.

    亚型

    Ig Fraction
  • 应用备注

    IF: 1:25. WB: 1:2000. IHC-P: 1:25. FC: 1:25

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))

    别名

    HSD17B10

    背景

    Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

    分子量

    26923

    UniProt

    Q99714
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