GRB14 抗体 (AA 14-48)
Quick Overview for GRB14 抗体 (AA 14-48) (ABIN6243218)
抗原
See all GRB14 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 14-48
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This GRB14 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 14-48 amino acids from the human region of human GRB14.
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亚型
- Ig Fraction
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anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 294-397) antibody
GRB14 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (Internal Region) antibodyGRB14 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 221-320) antibodyGRB14 适用: 人 ELISA, IF (cc), IF (p), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) antibodyGRB14 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (Internal Region) antibodyGRB14 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Growth Factor Receptor-Bound Protein 14 (GRB14) (AA 251-300) antibodyGRB14 适用: 人, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF: 1:25. WB: 1:1000. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- GRB14 (Growth Factor Receptor-Bound Protein 14 (GRB14))
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别名
- GRB14
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背景
- Adapter protein which modulates coupling of cell surface receptor kinases with specific signaling pathways. Binds to, and suppresses signals from, the activated insulin receptor (INSR). Potent inhibitor of insulin-stimulated MAPK3 phosphorylation. Plays a critical role regulating PDPK1 membrane translocation in response to insulin stimulation and serves as an adapter protein to recruit PDPK1 to activated insulin receptor, thus promoting PKB/AKT1 phosphorylation and transduction of the insulin signal.
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分子量
- 60988
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UniProt
- Q14449
抗原
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