电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Dynamin 1-Like 抗体 (C-Term)

This anti-Dynamin 1-Like antibody is a 兔 多克隆 antibody detecting Dynamin 1-Like in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN6243175
发货至: 中国

Quick Overview for Dynamin 1-Like 抗体 (C-Term) (ABIN6243175)

抗原

See all Dynamin 1-Like (DNM1L) 抗体
Dynamin 1-Like (DNM1L)

适用

  • 54
  • 44
  • 28
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 66
  • 9

克隆类型

  • 64
  • 11
多克隆

标记

  • 41
  • 5
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Dynamin 1-Like antibody is un-conjugated

应用范围

  • 40
  • 33
  • 25
  • 13
  • 13
  • 13
  • 10
  • 8
  • 6
  • 3
  • 3
  • 2
Western Blotting (WB)

克隆位点

RB52425
  • 抗原表位

    • 24
    • 11
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 513-547, C-Term

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This DNM1L antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 513-547 amino acids from the C-terminal region of human DNM1L.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:8000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    Dynamin 1-Like (DNM1L)

    别名

    DNM1L

    背景

    Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane- associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution.

    分子量

    81877

    UniProt

    O00429
You are here:
Chat with us!