BRCC3 抗体 (AA 36-70)
Quick Overview for BRCC3 抗体 (AA 36-70) (ABIN6243066)
抗原
See all BRCC3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 36-70
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This BRCC3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 36-70 amino acids from human BRCC3.
-
亚型
- Ig Fraction
-
-
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 14-316) antibody
BRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316), (N-Term) antibodyBRCC3 适用: 人 WB, IHC (p), EIA 宿主: 小鼠 Monoclonal AT3B1 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 18-50) antibodyBRCC3 适用: 人 WB 宿主: 兔 Polyclonal RB53911 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) antibody (FITC)BRCC3 适用: 人 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal FITC
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (C-Term) antibodyBRCC3 适用: 人, 小鼠, 大鼠, 马, Pig, 猴, Cow, 豚鼠, 兔, Bat, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (C-Term) antibodyBRCC3 适用: 人, 大鼠, 马, Pig, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 1-316) antibodyBRCC3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal AT3B1 unconjugated
anti-BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3) (AA 7-148) antibodyBRCC3 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
- BRCC3 (BRCA1/BRCA2-Containing Complex, Subunit 3 (BRCC3))
-
别名
- BRCC3
-
背景
- Metalloprotease that specifically cleaves 'Lys-63'- linked polyubiquitin chains. Does not have activity toward 'Lys- 48'-linked polyubiquitin chains. Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX, antagonizing the RNF8-dependent ubiquitination at double- strand breaks (DSBs). Catalytic subunit of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin in various substrates. Mediates the specific 'Lys-63'- specific deubiquitination associated with the COP9 signalosome complex (CSN), via the interaction of the BRISC complex with the CSN complex.
-
分子量
- 36072
-
UniProt
- P46736
-
途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
-
