BIRC6 抗体 (AA 4810-4844)
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北京 101111
Quick Overview for BIRC6 抗体 (AA 4810-4844) (ABIN6243063)
抗原
See all BIRC6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 4810-4844
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This BIRC6 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 4810-4844 amino acids from human BIRC6.
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亚型
- Ig Fraction
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anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) antibody
BIRC6 适用: 人, 小鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) (AA 4701-4857) antibodyBIRC6 适用: 人 ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) (C-Term) antibodyVerified BIRC6 适用: 人 IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 6 (BIRC6) (AA 4576-4857) antibodyBIRC6 适用: 人 IHC, WB, IP, ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- BIRC6 (Baculoviral IAP Repeat-Containing 6 (BIRC6))
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别名
- BIRC6
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背景
- Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also for the integrity of the midbody and the midbody ring, and its striking ubiquitin modification.
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分子量
- 530255
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UniProt
- Q9NR09
抗原
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