RGS19 抗体 (N-Term)
Quick Overview for RGS19 抗体 (N-Term) (ABIN6243052)
抗原
See all RGS19 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1-30, N-Term
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纯化方法
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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免疫原
- This RGS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-term of human RGS19.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. IHC-P: 1:50~100
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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: "Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 15, pp. 4731-6, (2015) (PubMed).
: "Activation of autophagy in mesenchymal stem cells provides tumor stromal support." in: Carcinogenesis, Vol. 32, Issue 7, pp. 964-72, (2011) (PubMed).
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: "Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 15, pp. 4731-6, (2015) (PubMed).
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- RGS19 (Regulator of G-Protein Signalling 19 (RGS19))
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别名
- RGS19
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背景
- Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). RGS19 enhances the intrinsic GTPase-activating protein activity of the Galphai3 protein, which stimulates autophagy by favoring the GDP-bound form of Galphai3.
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分子量
- 24636
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NCBI登录号
- NP_001034556, NP_005864
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UniProt
- P49795
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途径
- Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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