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RGS19 抗体 (N-Term)

This anti-RGS19 antibody is a 兔 多克隆 antibody detecting RGS19 in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 2+ publications.
产品编号 ABIN6243052
发货至: 中国

Quick Overview for RGS19 抗体 (N-Term) (ABIN6243052)

抗原

See all RGS19 抗体
RGS19 (Regulator of G-Protein Signalling 19 (RGS19))

适用

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宿主

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克隆类型

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多克隆

标记

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This RGS19 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB7576
  • 抗原表位

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    AA 1-30, N-Term

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This RGS19 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-term of human RGS19.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Li, Wang, Chen, Lu, Wang, Duan, Tian, Wang, You, Zou, Cheng, Zhu, Wan, Xi, Jiang, Han, Cao, Birnbaumer, Chu, Yang: "Gαi1 and Gαi3 regulate macrophage polarization by forming a complex containing CD14 and Gab1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 112, Issue 15, pp. 4731-6, (2015) (PubMed).

    Sanchez, Penfornis, Oskowitz, Boonjindasup, Cai, Dhule, Rowan, Kelekar, Krause, Pochampally: "Activation of autophagy in mesenchymal stem cells provides tumor stromal support." in: Carcinogenesis, Vol. 32, Issue 7, pp. 964-72, (2011) (PubMed).

  • 抗原

    RGS19 (Regulator of G-Protein Signalling 19 (RGS19))

    别名

    RGS19

    背景

    Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation. Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole). RGS19 enhances the intrinsic GTPase-activating protein activity of the Galphai3 protein, which stimulates autophagy by favoring the GDP-bound form of Galphai3.

    分子量

    24636

    NCBI登录号

    NP_001034556, NP_005864

    UniProt

    P49795

    途径

    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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