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WNK1 抗体 (AA 1848-1882)

This anti-WNK1 antibody is a 兔 多克隆 antibody detecting WNK1 in WB. Suitable for 人.
产品编号 ABIN6242959
发货至: 中国

Quick Overview for WNK1 抗体 (AA 1848-1882) (ABIN6242959)

抗原

See all WNK1 抗体
WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

适用

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宿主

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克隆类型

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多克隆

标记

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This WNK1 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB56242
  • 抗原表位

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    AA 1848-1882

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This WNK1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1848-1882 amino acids from human WNK1.

    亚型

    IgG
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    WNK1 (WNK Lysine Deficient Protein Kinase 1 (WNK1))

    别名

    WNK1

    背景

    Serine/threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D and SGK1. Controls sodium and chloride ion transport by inhibiting the activity of WNK4, by either phosphorylating the kinase or via an interaction between WNK4 and the autoinhibitory domain of WNK1. WNK4 regulates the activity of the thiazide- sensitive Na-Cl cotransporter, SLC12A3, by phosphorylation. WNK1 may also play a role in actin cytoskeletal reorganization. Phosphorylates NEDD4L.

    分子量

    250794

    UniProt

    Q9H4A3
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