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Reticulon 4 抗体 (AA 28-58)

This anti-Reticulon 4 antibody is a 兔 多克隆 antibody detecting Reticulon 4 in WB. Suitable for 人.
产品编号 ABIN6242947
发货至: 中国
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Quick Overview for Reticulon 4 抗体 (AA 28-58) (ABIN6242947)

抗原

See all Reticulon 4 (RTN4) 抗体
Reticulon 4 (RTN4)

适用

  • 101
  • 56
  • 39
  • 5
  • 4
  • 4
  • 4
  • 4
  • 4
  • 3
  • 2
  • 2
  • 1
  • 1

宿主

  • 85
  • 13
  • 3
  • 3
  • 2
  • 2

克隆类型

  • 70
  • 38
多克隆

标记

  • 45
  • 5
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  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
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  • 1
  • 1
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This Reticulon 4 antibody is un-conjugated

应用范围

  • 77
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  • 28
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  • 19
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  • 15
  • 13
  • 6
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB)

克隆位点

RB54371
  • 抗原表位

    • 16
    • 15
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 28-58

    预测反应

    M, Rat

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RTN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 28-58 amino acids from human RTN4.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    Reticulon 4 (RTN4)

    别名

    RTN4

    背景

    Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilization of wiring and restriction of plasticity in the adult CNS. Regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex (By similarity). Isoform 2 reduces the anti-apoptotic activity of Bcl-xl and Bcl-2. This is likely consecutive to their change in subcellular location, from the mitochondria to the endoplasmic reticulum, after binding and sequestration. Isoform 2 and isoform 3 inhibit BACE1 activity and amyloid precursor protein processing.

    分子量

    129931

    UniProt

    Q9NQC3

    途径

    Neurotrophin Signaling Pathway, Regulation of Cell Size, SARS-CoV-2 Protein Interactome
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