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PI4KB 抗体 (N-Term)

This anti-PI4KB antibody is a 兔 多克隆 antibody detecting PI4KB in WB 和 IHC (p). Suitable for 人. This Primary Antibody has been cited in 1 publication.
产品编号 ABIN6242814
发货至: 中国

Quick Overview for PI4KB 抗体 (N-Term) (ABIN6242814)

抗原

See all PI4KB 抗体
PI4KB (Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB))

适用

  • 19
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宿主

  • 17
  • 2

克隆类型

  • 17
  • 2
多克隆

标记

  • 19
This PI4KB antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB1676
  • 抗原表位

    • 2
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    AA 20-51, N-Term

    预测反应

    B, M, Rat

    纯化方法

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    免疫原

    This PI4KCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 20-51 amino acids from the N-terminal region of human PI4KCB.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:1000. IHC-P: 1:50~100

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • Spickler, Lippens, Laberge, Desmeules, Bellavance, Garneau, Guo, Hucke, Leyssen, Neyts, Vaillancourt, Décor, OMeara, Franti, Gauthier: "Phosphatidylinositol 4-kinase III beta is essential for replication of human rhinovirus and its inhibition causes a lethal phenotype in vivo." in: Antimicrobial agents and chemotherapy, Vol. 57, Issue 7, pp. 3358-68, (2013) (PubMed).

  • 抗原

    PI4KB (Phosphatidylinositol 4-Kinase, Catalytic, beta (PI4KB))

    别名

    PI4KCB

    背景

    Phosphoinositides are pivotal precursors to important second messengers and as signaling and molecules. Phosphatidylinositol 4-kinases (PI4Ks) are are crucial regulators of the phosphoinsitide cascade. PI4KCB is a wortmannin-sensitive PI 4-kinase responsible for regulating the synthesis of agonist-sensitive pools of polyphosphoinositides. The cellular reservoir of PI4KCB is predominantly cytosolic, however the protein is is activated strongly by recruitment to the membrane to stimulate phosphatidylinositol 4,5-bisphosphate synthesis at the plasma membrane. PI4KCB contains an N-terminal lipid kinase unique domain, which is shared by members of both the PI3 kinase and PI4 kinase families, and a C-terminal catalytic domain, which defines this protein as a member of a much larger protein/lipid kinase family.

    分子量

    91379

    NCBI登录号

    NP_001185702, NP_001185703, NP_001185704, NP_002642

    UniProt

    Q9UBF8

    途径

    Inositol Metabolic Process
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