ZNF281 抗体 (AA 416-450)
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北京 101111
Quick Overview for ZNF281 抗体 (AA 416-450) (ABIN6242706)
抗原
See all ZNF281 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 416-450
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This ZNF281 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 416-450 amino acids from the Central region of human ZNF281.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- ZNF281 (Zinc Finger Protein 281 (ZNF281))
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别名
- ZNF281
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背景
- Transcription repressor that plays a role in regulation of embryonic stem cells (ESCs) differentiation. Required for ESCs differentiation and acts by mediating autorepression of NANOG in ESCs: binds to the NANOG promoter and promotes association of NANOG protein to its own promoter and recruits the NuRD complex, which deacetylates histones. Not required for establishement and maintenance of ESCs (By similarity). Represses the transcription of a number of genes including GAST, ODC1 and VIM. Binds to the G- rich box in the enhancer region of these genes.
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分子量
- 96915
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UniProt
- Q9Y2X9
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途径
- Embryonic Body Morphogenesis
抗原
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