CREB3 抗体 (C-Term)
Quick Overview for CREB3 抗体 (C-Term) (ABIN6242675)
抗原
See all CREB3 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 311-344, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This CREB3 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 311-344 amino acids from the C-terminal region of human CREB3.
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亚型
- Ig Fraction
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anti-CAMP Responsive Element Binding Protein 3 (CREB3) (AA 273-371) antibody
CREB3 适用: 人 WB, ELISA, IHC (p), RNAi 宿主: 小鼠 Monoclonal 3H5 unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) (AA 1-230) antibodyCREB3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) (AA 1-230) antibodyCREB3 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) (AA 1-371) antibodyCREB3 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) antibodyCREB3 适用: 人, 小鼠, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) (C-Term) antibodyCREB3 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) (AA 76-87) antibodyVerified CREB3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) (AA 180-229) antibodyCREB3 适用: 人, Cow, 犬, Pig, 兔, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) (C-Term) antibodyCREB3 适用: 人, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-CAMP Responsive Element Binding Protein 3 (CREB3) antibodyCREB3 适用: 人, 小鼠 IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:8000. WB: 1:8000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- CREB3 (CAMP Responsive Element Binding Protein 3 (CREB3))
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别名
- CREB3
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背景
- Endoplasmic reticulum (ER)-bound transcription factor that plays a role in the unfolded protein response (UPR). Involved in cell proliferation and migration, tumor suppression and inflammatory gene expression. Plays also a role in the human immunodeficiency virus type 1 (HIV-1) virus protein expression and in the herpes simplex virus-1 (HSV-1) latent infection and reactivation from latency. Isoform 2 plays a role in the unfolded protein response (UPR). Isoform 2 acts as a positive regulator of LKN-1/CCL15-induced chemotaxis signaling of leukocyte cell migration. Isoform 2 may play a role as a cellular tumor suppressor that is targeted by the hepatitis C virus (HSV) core protein. Isoform 2 represses the VP16-mediated transactivation of immediate early genes of the HSV-1 virus by sequestring host cell factor-1 HCFC1 in the ER membrane of sensory neurons, thereby preventing the initiation of the replicative cascade leading to latent infection. Isoform 3 functions as a negative transcriptional regulator in ligand-induced transcriptional activation of the glucocorticoid receptor NR3C1 by recruiting and activating histone deacetylases (HDAC1, HDAC2 and HDAC6). Isoform 3 decreases the acetylation level of histone H4. Isoform 3 does not promote the chemotactic activity of leukocyte cells.
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分子量
- 41379
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UniProt
- O43889
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途径
- Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, ER-Nucleus Signaling, Maintenance of Protein Location, Unfolded Protein Response
抗原
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