SRY 抗体 (AA 52-82)
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北京 101111
Quick Overview for SRY 抗体 (AA 52-82) (ABIN6242646)
抗原
See all SRY 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 52-82
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This SRY antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 52-82 amino acids from human SRY.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- SRY (Sex Determining Region Y (SRY))
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别名
- SRY
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背景
- Transcriptional regulator that controls a genetic switch in male development. It is necessary and sufficient for initiating male sex determination by directing the development of supporting cell precursors (pre-Sertoli cells) as Sertoli rather than granulosa cells (By similarity). In male adult brain involved in the maintenance of motor functions of dopaminergic neurons (By similarity). Involved in different aspects of gene regulation including promoter activation or repression (By similarity). Promotes DNA bending. SRY HMG box recognizes DNA by partial intercalation in the minor groove. Also involved in pre-mRNA splicing. Binds to the DNA consensus sequence 5'-[AT]AACAA[AT]-3'.
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分子量
- 23884
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UniProt
- Q05066
抗原
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