RIN1 抗体 (AA 20-70)
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北京 101111
Quick Overview for RIN1 抗体 (AA 20-70) (ABIN6242616)
抗原
See all RIN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 20-70
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 20-70 amino acids from human.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- RIN1 (Ras and Rab Interactor 1 (RIN1))
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别名
- RIN1
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背景
- Ras effector protein, which may serve as an inhibitory modulator of neuronal plasticity in aversive memory formation. Can affect Ras signaling at different levels. First, by competing with RAF1 protein for binding to activated Ras. Second, by enhancing signaling from ABL1 and ABL2, which regulate cytoskeletal remodeling. Third, by activating RAB5A, possibly by functioning as a guanine nucleotide exchange factor (GEF) for RAB5A, by exchanging bound GDP for free GTP, and facilitating Ras-activated receptor endocytosis.
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分子量
- 84099
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UniProt
- Q13671
抗原
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