RNF7 抗体 (N-Term)
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北京 101111
Quick Overview for RNF7 抗体 (N-Term) (ABIN6242612)
抗原
See all RNF7 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 25-57, N-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This RNF7 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 25-57 amino acids from the N-terminal region of human RNF7.
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亚型
- Ig Fraction
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应用备注
- WB: 1:8000. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- RNF7 (Ring Finger Protein 7 (RNF7))
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别名
- RNF7
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背景
- Probable component of the SCF (SKP1-CUL1-F-box protein) E3 ubiquitin ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Through the RING-type zinc finger, seems to recruit the E2 ubiquitination enzyme to the complex and brings it into close proximity to the substrate. Promotes the neddylation of CUL5 via its interaction with UBE2F. May play a role in protecting cells from apoptosis induced by redox agents.
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分子量
- 12683
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UniProt
- Q9UBF6
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途径
- Positive Regulation of Endopeptidase Activity
抗原
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