TNIK 抗体 (Ser764)
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北京 101111
Quick Overview for TNIK 抗体 (Ser764) (ABIN6242564)
抗原
See all TNIK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- Ser764
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This TNIK(S764) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human TNIK(S764).
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亚型
- IgG
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应用备注
- WB: 1:500. WB: 1:500. IHC-P-Leica: 1:500
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- TNIK (TRAF2 and NCK Interacting Kinase (TNIK))
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别名
- TNIK
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背景
- Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.
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分子量
- 154943
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UniProt
- Q9UKE5
抗原
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