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TNIK 抗体 (Ser764)

This anti-TNIK antibody is a 兔 多克隆 antibody detecting TNIK in WB 和 IHC (p). Suitable for 人 和 小鼠.
产品编号 ABIN6242564
发货至: 中国

Quick Overview for TNIK 抗体 (Ser764) (ABIN6242564)

抗原

See all TNIK 抗体
TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

适用

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人, 小鼠

宿主

  • 86
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克隆类型

  • 86
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多克隆

标记

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This TNIK antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB59089
  • 抗原表位

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    Ser764

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This TNIK(S764) antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between amino acids from the human region of human TNIK(S764).

    亚型

    IgG
  • 应用备注

    WB: 1:500. WB: 1:500. IHC-P-Leica: 1:500

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    TNIK (TRAF2 and NCK Interacting Kinase (TNIK))

    别名

    TNIK

    背景

    Serine/threonine kinase that acts as an essential activator of the Wnt signaling pathway. Recruited to promoters of Wnt target genes and required to activate their expression. May act by phosphorylating TCF4/TCF7L2. Appears to act upstream of the JUN N-terminal pathway. May play a role in the response to environmental stress. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it may play a role in cytoskeletal rearrangements and regulate cell spreading. Phosphorylates SMAD1 on Thr-322.

    分子量

    154943

    UniProt

    Q9UKE5
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