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RNF139 抗体 (AA 604-636)

The 兔 多克隆 anti-RNF139 antibody is suitable to detect RNF139 in samples from 人. It has been validated for WB.
产品编号 ABIN6242550
发货至: 中国
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Quick Overview for RNF139 抗体 (AA 604-636) (ABIN6242550)

抗原

See all RNF139 抗体
RNF139 (Ring Finger Protein 139 (RNF139))

适用

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宿主

  • 28
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克隆类型

  • 30
  • 3
多克隆

标记

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This RNF139 antibody is un-conjugated

应用范围

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Western Blotting (WB)

克隆位点

RB54248
  • 抗原表位

    • 15
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    AA 604-636

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This RNF139 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 604-636 amino acids from human RNF139.

    亚型

    Ig Fraction
  • 应用备注

    WB: 1:2000

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    有效期

    6 months
  • 抗原

    RNF139 (Ring Finger Protein 139 (RNF139))

    别名

    RNF139

    背景

    E3-ubiquitin ligase, acts as a negative regulator of the cell proliferation through mechanisms involving G2/M arrest and cell death. Required for MHC class I ubiquitination in cells expressing the cytomegalovirus protein US2 before dislocation from the endoplasmic reticulum (ER). Affects SREBP processing by hindering the SREBP/SCAP complex translocation from the ER to the Golgi, thereby reducing SREBF2 target gene expression. Required for INSIG1 ubiquitination. May be required for EIF3 complex ubiquitination. May function as a signaling receptor.

    分子量

    75994

    UniProt

    Q8WU17
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