PFN1 抗体 (AA 108-140)
Quick Overview for PFN1 抗体 (AA 108-140) (ABIN6242521)
抗原
See all PFN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 108-140
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预测反应
- B
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This Profilin-1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 108-140 amino acids from the human region of human Profilin-1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. FC: 1:25. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- PFN1 (Profilin 1 (PFN1))
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别名
- Profilin-1
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背景
- Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G-actin is essential for its inhibition of AR.
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分子量
- 15054
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UniProt
- P07737
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途径
- Regulation of Actin Filament Polymerization, Tube Formation, Maintenance of Protein Location
抗原
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