MED15 抗体 (C-Term)
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北京 101111
Quick Overview for MED15 抗体 (C-Term) (ABIN6242465)
抗原
See all MED15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 712-746, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This mouse Med15 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 712-746 amino acids from the C-terminal region of mouse Med15.
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亚型
- Ig Fraction
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应用备注
- WB: 1:1000. WB: 1:2000. IHC-P: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- MED15 (Mediator Complex Subunit 15 (MED15))
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别名
- Med15
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背景
- Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. Required for cholesterol-dependent gene regulation. Positively regulates the Nodal signaling pathway (By similarity).
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分子量
- 86607
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UniProt
- Q924H2
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途径
- Stem Cell Maintenance, Regulation of Lipid Metabolism by PPARalpha
抗原
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