IL-11 抗体 (AA 27-61)
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北京 101111
Quick Overview for IL-11 抗体 (AA 27-61) (ABIN6242412)
抗原
See all IL-11 (IL11) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 27-61
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This IL11 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 27-61 amino acids from human IL11.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000. FC: 1:25
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- IL-11 (IL11) (Interleukin 11 (IL11))
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别名
- IL11
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背景
- Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production (PubMed:< a href="http://www.uniprot.org/citations/2145578" target="_blank">2145578). Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation (PubMed:< a href="http://www.uniprot.org/citations/12919066" target="_blank">12919066). Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3.
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分子量
- 21429
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UniProt
- P20809
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途径
- JAK/STAT Signaling, Negative Regulation of Hormone Secretion
抗原
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