XRN1 抗体 (C-Term)
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北京 101111
Quick Overview for XRN1 抗体 (C-Term) (ABIN6242394)
抗原
See all XRN1 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 1389-1423, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This XRN1 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1389-1423 amino acids from the C-terminal region of human XRN1.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- XRN1 (5'-3' Exoribonuclease 1 (XRN1))
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别名
- XRN1
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背景
- Major 5'-3' exoribonuclease involved in mRNA decay. Required for the 5'-3'-processing of the G4 tetraplex-containing DNA and RNA substrates. The kinetic of hydrolysis is faster for G4 RNA tetraplex than for G4 DNA tetraplex and monomeric RNA tetraplex. Binds to RNA and DNA (By similarity). Plays a role in replication-dependent histone mRNA degradation. May act as a tumor suppressor protein in osteogenic sarcoma (OGS).
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分子量
- 194107
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UniProt
- Q8IZH2
抗原
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