FOXN4 抗体 (C-Term)
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Quick Overview for FOXN4 抗体 (C-Term) (ABIN6242346)
抗原
See all FOXN4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 436-470, C-Term
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纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
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免疫原
- This FOXN4 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 436-470 amino acids from the C-terminal region of human FOXN4.
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亚型
- Ig Fraction
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应用备注
- WB: 1:2000
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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有效期
- 6 months
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- FOXN4 (Forkhead Box N4 (FOXN4))
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别名
- FOXN4
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背景
- Transcription factor essential for neural and some non- neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5'-ACGC-3'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4- NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).
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分子量
- 55215
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UniProt
- Q96NZ1
抗原
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