ANKRD15 抗体
Quick Overview for ANKRD15 抗体 (ABIN6242162)
抗原
See all ANKRD15 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- This antibody is purified through a protein G column, followed by dialysis against PBS.
-
免疫原
- This KANK1 antibody is generated from a mouse immunized with a recombinant protein of human KANK1.
-
亚型
- IgG1 kappa
-
-
anti-Ankyrin Repeat Domain 15 (ANKRD15) (AA 701-800) antibody
ANKRD15 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2B8 unconjugated
anti-Ankyrin Repeat Domain 15 (ANKRD15) (AA 66-255) antibodyANKRD15 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ankyrin Repeat Domain 15 (ANKRD15) (AA 900-1000) antibodyANKRD15 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:2000. IHC-P: 1:25
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
- ANKRD15 (Ankyrin Repeat Domain 15 (ANKRD15))
-
别名
- KANK1
-
背景
- Involved in the control of cytoskeleton formation by regulating actin polymerization. Inhibits actin fiber formation and cell migration. Inhibits RhoA activity, the function involves phosphorylation through PI3K/Akt signaling and may depend on the competetive interaction with 14-3-3 adapter proteins to sequester them from active complexes. Inhibits the formation of lamellipodia but not of filopodia, the function may depend on the competetive interaction with BAIAP2 to block its association with activated RAC1. Inhibits fibronectin-mediated cell spreading, the function is partially mediated by BAIAP2. Inhibits neurite outgrowth. Involved in the establishment and persistence of cell polarity during directed cell movement in wound healing. In the nucleus, is involved in beta-catenin-dependent activation of transcription. Potential tumor suppressor for renal cell carcinoma.
-
分子量
- 147289
-
UniProt
- Q14678
-
途径
- Regulation of Actin Filament Polymerization
抗原
-
