PEG10
适用: 人, 小鼠
WB, IF (cc), IF (p)
宿主: 兔
Polyclonal
Cy5.5
应用备注
IP: 1:500. WB: 1:1000
限制
仅限研究用
状态
Liquid
储存条件
4 °C,-20 °C
抗原
PEG10
(Paternally Expressed 10 (PEG10))
别名
PEG10
背景
Prevents apoptosis in hepatocellular carcinoma (HCC) cells through interaction with SIAH1, a mediator of apoptosis. May also have a role in cell growth promotion and hepatoma formation. Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1. When overexpressed, induces the formation of cellular extension, such as filipodia in association with ALK1. Involved at the immediate early stage of adipocyte differentiation (By similarity). May bind to the 5'-GCCTGTCTTT-3' DNA sequence of the MB1 domain in the myelin basic protein (MBP) promoter (By similarity).