JMJD6 抗体 (N-Term)
Quick Overview for JMJD6 抗体 (N-Term) (ABIN6241759)
抗原
See all JMJD6 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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免疫原
- Recombinant Protein
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anti-Jumonji Domain Containing 6 (JMJD6) (AA 1-334) antibody
JMJD6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (Center) antibodyJMJD6 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (AA 1-320) antibodyJMJD6 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (AA 2-100) antibodyJMJD6 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (AA 214-263) antibodyJMJD6 适用: 人, 斑马鱼, 非洲爪蟾, Bat WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (N-Term) antibodyJMJD6 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (AA 296-345) antibodyJMJD6 适用: 人, Cow, 犬, 马, 小鸡, Pig, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (N-Term) antibodyJMJD6 适用: 人, 小鼠, 大鼠, Cow, 犬, 马, 豚鼠, 小鸡, Bat, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (C-Term) antibodyJMJD6 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Jumonji Domain Containing 6 (JMJD6) (Middle Region) antibodyJMJD6 适用: 人, 小鼠, 大鼠, Cow, 犬, 斑马鱼, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000. ICC: 1:200
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C,-20 °C
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- JMJD6 (Jumonji Domain Containing 6 (JMJD6))
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别名
- JMJD6
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背景
- Dioxygenase that can both act as a histone arginine demethylase and a lysyl-hydroxylase. Acts as a lysyl-hydroxylase that catalyzes 5-hydroxylation on specific lysine residues of target proteins such as U2AF2/U2AF65 and LUC7L2. Acts as a regulator of RNA splicing by mediating 5-hydroxylation of U2AF2/U2AF65, affecting the pre-mRNA splicing activity of U2AF2/U2AF65. In addition to peptidyl-lysine 5-dioxygenase activity, may act as an RNA hydroxylase, as suggested by its ability to bind single strand RNA. Also acts as an arginine demethylase which demethylates histone H3 at 'Arg-2' (H3R2me) and histone H4 at 'Arg-3' (H4R3me), thereby playing a role in histone code. However, histone arginine demethylation may not constitute the primary activity in vivo. Has no histone lysine demethylase activity. Required for differentiation of multiple organs during embryogenesis. Acts as a key regulator of hematopoietic differentiation: required for angiogenic sprouting by regulating the pre-mRNA splicing activity of U2AF2/U2AF65. Seems to be necessary for the regulation of macrophage cytokine responses.
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UniProt
- Q6NYC1
抗原
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