SOX2 抗体
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北京 101111
Quick Overview for SOX2 抗体 (ABIN6241700)
抗原
See all SOX2 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- Recombinant Protein
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应用备注
- WB: 1:1000. FC: 1:100. ICC: 1:150
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C,-20 °C
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- SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
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别名
- Sox2
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背景
- Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).
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UniProt
- P48431
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途径
- Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
抗原
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