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CBX3 抗体

This anti-CBX3 antibody is a 小鼠 单克隆 antibody detecting CBX3 in WB, IHC, IP 和 ICC. Suitable for 人 和 小鼠.
产品编号 ABIN6241538
发货至: 中国

Quick Overview for CBX3 抗体 (ABIN6241538)

抗原

See all CBX3 抗体
CBX3 (Chromobox Homolog 3 (CBX3))

适用

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人, 小鼠

宿主

  • 82
  • 25
  • 2
小鼠

克隆类型

  • 75
  • 34
单克隆

标记

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This CBX3 antibody is un-conjugated

应用范围

  • 56
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  • 9
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  • 1
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Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
  • 免疫原

    Recombinant Protein
  • 应用备注

    IP: 1:500. WB: 1:1000. IHC: 1:100. ICC: 1:200

    限制

    仅限研究用
  • 状态

    Liquid

    储存条件

    4 °C,-20 °C
  • 抗原

    CBX3 (Chromobox Homolog 3 (CBX3))

    别名

    HP1-gamma

    背景

    Seems to be involved in transcriptional silencing in heterochromatin-like complexes. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. May contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin-like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the mehtyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box elements of the circadian target genes such as PER2 itself or PER1.

    UniProt

    Q13185
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