SAFB
适用: 小鼠, 大鼠
IF (p), IF (cc)
宿主: 兔
Polyclonal
AbBy Fluor® 350
应用备注
WB: 1:1000. ICC: 1:200
限制
仅限研究用
状态
Liquid
储存条件
4 °C,-20 °C
抗原
SAFB
(Scaffold Attachment Factor B (SAFB))
别名
SAFB1
背景
Binds to scaffold/matrix attachment region (S/MAR) DNA and forms a molecular assembly point to allow the formation of a 'transcriptosomal' complex (consisting of SR proteins and RNA polymerase II) coupling transcription and RNA processing (By similarity). Can function as an estrogen receptor corepressor and can also bind to the HSP27 promoter and decrease its transcription. When associated with RBMX, binds to and stimulates transcription from the SREBF1 promoter (By similarity). Can inhibit cell proliferation.