WDR77 抗体
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北京 101111
Quick Overview for WDR77 抗体 (ABIN6241347)
抗原
See all WDR77 抗体适用
宿主
克隆类型
标记
应用范围
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免疫原
- Recombinant Protein
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应用备注
- WB: 1:1000. ICC: 1:100
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C,-20 °C
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- WDR77 (WD Repeat Domain 77 (WDR77))
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别名
- WDR77
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背景
- Non-catalytic component of the 20S PRMT5-containing methyltransferase complex, which modifies specific arginines to dimethylarginines in several spliceosomal Sm proteins and histones. This modification targets Sm proteins to the survival of motor neurons (SMN) complex for assembly into small nuclear ribonucleoprotein core particles. Might play a role in transcription regulation. The 20S PRMT5-containing methyltransferase complex also methylates the Piwi proteins (PIWIL1, PIWIL2 and PIWIL4), methylation of Piwi proteins being required for the interaction with Tudor domain-containing proteins and subsequent localization to the meiotic nuage.
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UniProt
- Q9BQA1
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途径
- Ribonucleoprotein Complex Subunit Organization
抗原
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