LC3A / LC3B 抗体
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北京 101111
Quick Overview for LC3A / LC3B 抗体 (ABIN6241232)
抗原
适用
宿主
克隆类型
标记
应用范围
克隆位点
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anti-LC3A / LC3B antibody
适用: 小鼠, 人, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-LC3A / LC3B (AA 31-121) antibody适用: 小鼠 IF (cc), IF (p), ELISA, IHC (fro), IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-LC3A / LC3B antibody适用: 小鼠, 人, 大鼠 IF 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000
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限制
- 仅限研究用
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状态
- Liquid
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储存条件
- 4 °C,-20 °C
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- LC3A / LC3B
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别名
- LC3A/B
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背景
- LC3A:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes) (PubMed:20713600, PubMed:24290141). Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (PubMed:20713600). LC3B:Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway.
抗原
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