Catenin alpha 1/2 抗体
This anti- antibody is a 兔 多克隆 antibody detecting in WB. Suitable for 人, 小鼠 和 大鼠.
1 image
Quick Overview for Catenin alpha 1/2 抗体 (ABIN6241202)
抗原
Catenin alpha 1/2
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
非结合性
应用范围
Western Blotting (WB)
-
-
免疫原
- synthetic peptide
-
-
anti-Catenin alpha 1/2 (C-Term) antibody
适用: 人, 小鼠, 大鼠, 小鸡, Pig WB, IHC 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 1:1000
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
储存条件
- 4 °C,-20 °C
-
-
- Catenin alpha 1/2
-
背景
- Associates with the cytoplasmic domain of a variety of cadherins. The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Can associate with both E- and N-cadherins. Originally believed to be a stable component of E-cadherin/catenin adhesion complexes and to mediate the linkage of cadherins to the actin cytoskeleton at adherens junctions. In contrast, cortical actin was found to be much more dynamic than E-cadherin/catenin complexes and CTNNA1 was shown not to bind to F-actin when assembled in the complex suggesting a different linkage between actin and adherens junctions components. The homodimeric form may regulate actin filament assembly and inhibit actin branching by competing with the Arp2/3 complex for binding to actin filaments. May play a crucial role in cell differentiation.
-
UniProt
- P35221
抗原
-
You are here:
