PDGFRB 抗体 (pTyr579)
Quick Overview for PDGFRB 抗体 (pTyr579) (ABIN6241032)
抗原
See all PDGFRB 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- pTyr579
-
预测反应
- C, Zf, M, Rat, X
-
纯化方法
- This antibody is purified through a protein A column, followed by peptide affinity purification.
-
免疫原
- This Phospho-PDGFR-Y579 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y579 of human PDGFR.
-
亚型
- Ig Fraction
-
-
-
-
应用备注
- IHC-P: 1:50~100
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
缓冲液
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
有效期
- 6 months
-
-
-
An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway. ..." in: Cancer discovery, Vol. 1, Issue 5, pp. 442-56, (2012) (PubMed).
: "
-
An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR-dependent pathway. ..." in: Cancer discovery, Vol. 1, Issue 5, pp. 442-56, (2012) (PubMed).
-
- PDGFRB (Platelet Derived Growth Factor Receptor beta (PDGFRB))
-
别名
- PDGFR
-
背景
- PDGFR is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. The gene for this protein is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor, all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETS, leukemia gene, results in chronic myelomonocytic leukemia.
-
分子量
- 123968
-
NCBI登录号
- NP_002600
-
UniProt
- P09619
-
途径
- Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Inositol Metabolic Process, Glycosaminoglycan Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling
抗原
-