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HLA-A+B+C+E 抗体 (PE)

This 小鼠 单克隆 antibody specifically detects HLA-A+B+C+E in FACS. It exhibits reactivity toward 人.
产品编号 ABIN6240830
发货至: 中国
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Quick Overview for HLA-A+B+C+E 抗体 (PE) (ABIN6240830)

抗原

HLA-A+B+C+E

适用

宿主

  • 1
小鼠

克隆类型

  • 1
单克隆

标记

  • 1
PE

应用范围

  • 1
  • 1
  • 1
Flow Cytometry (FACS)

克隆位点

TP25-99SF
  • 原理

    Anti-HLA-ABCE PE

    特异性

    The mouse monoclonal antibody TP25.99SF recognizes an extracellular epitope on HLA-ABC and HLA-E molecules, but not HLA-G. It can be used for discrimination between HLA-G and other HLA-class I antigens.

    交叉反应 (详细)

    Human

    纯化方法

    Purified antibody is conjugated with R-phycoerythrin (PE) under optimum conditions. Unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

    免疫原

    IFN-gamma-treated human melanoma cells Colo 38

    亚型

    IgG1
  • 应用备注

    Flow cytometry: Recommended dilution: 1-5 μg/mL.

    限制

    仅限研究用
  • 浓度

    0.1 mg/mL

    缓冲液

    Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography.

    储存条件

    4 °C

    储存方法

    Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.
  • 抗原

    HLA-A+B+C+E

    别名

    HLA-ABCE

    背景

    HLA-class I major histocompatibility (MHC) antigens are intrinsic membrane glycoproteins expressed on nucleated cells and noncovalently associated with an invariant beta2 microglobulin. They carry foreign determinants important for immune recognition by cytotoxic T cells, thus important for anti-viral and anti-tumour defence. Classical human HLA-class I antigens are represented by HLA-A, HLA-B and HLA-C molecules, the non-classical by e.g. HLA-E, HLA-G.
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