INPP5D 抗体 (AA 959-1188)
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北京 101111
Quick Overview for INPP5D 抗体 (AA 959-1188) (ABIN6213625)
抗原
See all INPP5D 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 959-1188
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序列
- SPPTPPGQPP ISPKKFLPST ANRGLPPRTQ ESRPSDLGKN AGDTLPQEDL PLTKPEMFEN PLYGSLSSFP KPAPRKDQES PKMPRKEPPP CPEPGILSPS IVLTKAQEAD RGEGPGKQVP APRLRSFTCS SSAEGRAAGG DKSQGKPKTP VSSQAPVPAK RPIKPSRSEI NQQTPPTPTP RPPLPVKSPA VLHLQHSKGR DYRDNTELPH HGKHRPEEGP PGPLGRTAMQ
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交叉反应
- 人, 小鼠, 大鼠
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产品特性
- Polyclonal Antibodies
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纯化方法
- Affinity purification
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免疫原
- Recombinant fusion protein containing a sequence corresponding to amino acids 959-1188 of human SHIP1 (NP_005532.2).
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亚型
- IgG
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anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibody
INPP5D 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Monoclonal 9G11 unconjugated Recombinant Antibody
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) antibodyINPP5D 适用: 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (pTyr1021) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (N-Term) antibodyINPP5D 适用: 人 WB, ICC, ICFC 宿主: 小鼠 Monoclonal SHIP-01 unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠, 猴, Cow, 犬, 豚鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D) (C-Term) antibodyINPP5D 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200
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限制
- 仅限研究用
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缓冲液
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Avoid freeze / thaw cycles.
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- INPP5D (Inositol Polyphosphate-5-Phosphatase, 145kDa (INPP5D))
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别名
- INPP5D
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背景
- This gene is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes a protein with an N-terminal SH2 domain, an inositol phosphatase domain, and two C-terminal protein interaction domains. Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation. At the plasma membrane, the protein hydrolyzes the 5' phosphate from phosphatidylinositol (3,4,5)-trisphosphate and inositol-1,3,4,5-tetrakisphosphate, thereby affecting multiple signaling pathways. The protein is also partly localized to the nucleus, where it may be involved in nuclear inositol phosphate signaling processes. Overall, the protein functions as a negative regulator of myeloid cell proliferation and survival. Mutations in this gene are associated with defects and cancers of the immune system. Alternative splicing of this gene results in multiple transcript variants.,INPP5D,SHIP,SHIP-1,SHIP1,SIP-145,hp51CN,p150Ship,Epigenetics & Nuclear Signaling,Signal Transduction,Cell Biology & Developmental Biology,Apoptosis,Endocrine & Metabolism,Lipid Metabolism,Insulin Receptor Signaling Pathway,Immunology & Inflammation,B Cell Receptor Signaling Pathway,INPP5D
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分子量
- 109 kDa/133 kDa
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基因ID
- 3635
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UniProt
- Q92835
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途径
- TCR Signaling, BCR Signaling, Warburg Effect
抗原
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