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Testosterone 抗体

ELISA, IHC, Coat, ISt 宿主: 小鼠 Monoclonal 4E1G2 unconjugated
产品编号 ABIN6189877
发货至: 中国
  • 抗原 See all Testosterone 抗体
    Testosterone
    适用
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    宿主
    • 28
    • 9
    • 3
    小鼠
    克隆类型
    • 28
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    单克隆
    标记
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    This Testosterone antibody is un-conjugated
    应用范围
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    ELISA, Immunohistochemistry (IHC), Coating (Coat), Immunostaining (ISt)
    原理
    Mouse Monoclonal anti-Testosterone (4E1G2), Purified, BSA-free
    产品特性
    This MAb is highly specific to testosterone. Its affinity constant for testosterone is ~1010 M-1. In competitive binding immunoassay, it reacts with testosterone 100 % , 11-beta-hydroxy testosterone 3.3 %, 17-alpha-methyl testosterone <0.1 %, 5-alpha DHT 0.8 %, estradiol <0.1 % and progesterone <0.1 %. Testosterone, a steroid hormone from the androgen group, is derived from cholesterol. Testosterone is primarily secreted in the testes, but the ovaries and adrenal glands also produce smaller amounts. It is the principal male sex hormone and is responsible for the maturation of sex organs and the development of male secondary sex characteristics. The hormone is also involved in the growth of muscle mass and increases bone density and maturation. It functions by activating the androgen receptor and converting to estradiol and activation of estrogen receptors. Testosterone has been employed therapeutically to treat many conditions including infertility, lack of libido, osteoporosis, height growth and bone marrow stimulation. Anti-testosterone antibody may also prove useful in identification of testicular tumors arising from interstitial cells. Primary antibodies are available purified, or with a selection of fluorescent CF® dyes and other labels. CF® dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
    纯化方法
    Purified
    免疫原
    Testosterone 3 CMO conjugated to BSA
    克隆位点
    4E1G2
    亚型
    IgG1 kappa
    Top Product
    Discover our top product Testosterone Primary Antibody
  • 应用备注
    Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM citrate buffer  pH 6.0 for 10-20 min followed by cooling at RT for 20 min
    • Immunohistology formalin-paraffin 0.25-0.5 μg/mL
    • ELISA For coating, order Ab without BSA
    • Optimal dilution for a specific application should be determined by user
    说明

    Interstitial or Leydid cells in testis.

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS (no BSA, no azide)
    储存液
    Azide free
  • 抗原
    Testosterone
    Abstract
    Testosterone 产品
    物质类
    Hormone
    背景
    17i²-Hydroxy-3-oxo-4-androstene, 17i²-Hydroxy-4-androsten-3-one, 4-Androsten-17i²-ol-3-one, trans-Testosterone
    分子量
    288.42Da
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